Malignant Hyperthermia (MH)
"Also known as Canine Stress Syndrome, dogs affected with MH develop an elevated body temperature, muscle contractions and rigidity and sometimes seizures. Affected dogs appear generally healthy, but under stressful situations can manifest the disease. Most importantly, exposure to anesthetics and muscle relaxants stimulate MH, making it very important to know if animals are normal before surgery or medical treatment."
"MH is autosomal dominant, meaning that animals with just one copy of this allele will be affected. 50% of their offspring will also be affected...Affected animals should not be used for breeding."
"Many breeds, especially Border Collie, English Springer Spaniel, Greyhound, Irish Wolfhound, and Labrador Retriever."